Some of the most common side effects of Robaxin methocarbamol abuse include: Drowsiness.
It may also be useful for treating seizures and muscle spasms associated with the ingestion of a toxic substance in cats and dogs. Methocarbamol is considered a supplementary medication in the treatment of opioid or opiate withdrawal. It targets specific symptoms, such as muscle cramps and spasms. Methocarbamol dosage depends on a variety of factors. Methocarbamol is available in and milligram mg tablets. For adults with muscle stiffness, the typical dosage is 1, mg, four times daily.
Research assessing the effects of methocarbamol among children under 16 years is limited. If your child has been prescribed methocarbamol, follow the dosage instructions from your doctor. Compared to other medicines, Robaxin is a less sedating alternative. The pill is the only approved muscle relaxant approved by the European Medicines Agency for lower back pain.
This is because other muscle relaxants like tetrazepam were withdrawn due to unfavorable risk-benefit factors. However, it is not advisable to combine taking this drug with alcohol. This is because it is a CNS depressant and taking it with alcohol may have dire consequences. Methocarbamol For Tetanus Robaxin can also be used to treat tetanus. Clinical tests suggest that the neuromuscular manifestations of tetanus can be controlled by Methocarbamol.
In a study, it was discovered that when muscle relaxants were used to help treat tetanus patients, there was a heavy improvement in the recovery rate.
There was a major reduction between spasms and complications were greatly reduced. However, it does not replace the regular procedures and medicines used to treat tetanus like debridement, penicillin, and tetanus antitoxin. Off-Label Methocarbamol Uses Though Methocarbamol Robaxin is used as a musculoskeletal relaxant it can also be a helpful supplemental medication.
Here are some off-label Methocarbamol uses: myofascial pain, fibromyalgia, inflammatory arthritides, acute and non-specific low back pain, rib fractures, perioperative care of knee and hip replacements, and abdominal muscle cramps in patients with cirrhosis.
In the past, the Methocarbamol pill was useful in treating tetanus, but that has been replaced by benzodiazepines. Note that the medication is ineffective in the treatment of rigidity, contracture, or spasticity which emanates from an injury to the upper motor neuron. In the case of any of these medical conditions, contact a physician for help.
Methocarbamol For Opiate Withdrawal Some people may ask whether the Methocarbamol pill works for opiate withdrawal. Since it is also known to be a central nervous system depressant, as it has sedating properties, it relaxes the mind and the body.
Hence people often use the medication to ease their opiate withdrawal symptoms , such as anxiety, insomnia, gastrointestinal distress, restless leg syndrome RLS , muscle aches and pains. The use of Methocarbamol has proven to be quite beneficial when treating opiate withdrawal symptoms for most people. However, sometimes it has no effect or could even give an adverse reaction.
Methocarbamol For Sleep Since Robaxin possesses sedative properties, it eases the mind and relaxes the body and is therefore sometimes used to induce sleep. It works by stopping pain-related sensory signals from reaching the brain and so it is also used to treat headaches, in addition to just back pain.
Studies have shown that migraines cause muscle contractions, that is why some people rub their temples to feel some relief. CNS depressants do not work directly on the muscles. They work on the nerve endings and, therefore, the brain mechanisms of migraines, which is why a Robaxin pill may be used to treat migraines. Methocarbamol For Anxiety People often ask, does Robaxin work for anxiety? A central nervous system depressant works by relaxing the nerves in the body.
This is why muscle relaxants like methocarbamol and ibuprofen are used for anxiety relief and may be given before surgical procedures that may cause stress and anxiety. Robaxin for Fibromyalgia Patients with fibromyalgia suffer from musculoskeletal pain in different parts of their bodies.
Fibromyalgia affects the way the brain perceives pain signals by amplifying them. CNS depressants such as Robaxin help calm the nervous system by blocking these signals from reaching the brain and therefore it is proven to be useful for fibromyalgia patients as well.
Stopping Robaxin use should be done gradually, and with medical guidance to avoid relapse. When looking at the potential of Methocarbamol abuse, it is important to focus on previous studies that have been conducted on this subject.
Fortunately, a few scientific trials have provided the evidence. While Robaxin abuse is not as likely as with narcotics or opioid painkillers, studies show that this is still a possibility that needs to be kept in mind when using the drug. Is Robaxin addictive? In asking this question, people need to consider the dose of the drug that they are taking.
This is one particularly important factor that seems to play a role. Furthermore, Methocarbamol addiction also seems to depend on whether a person has a history of substance abuse. Overdosing on the medicine may come about as a result of combining it with alcohol. This may in turn lead to addiction. It is, therefore, advisable for patients to stay off alcohol while administering this medicine.
Methocarbamol addiction must be taken seriously according to the study conducted by researchers at the Johns Hopkins University School of Medicine. During the research, people were divided into three groups. One group received a daily dose of Methocarbamol. A second group received Lorazepam and a third a placebo drug.
Lorazepam had the most significant effect in terms of potential for abuse. The study found, however, that those who took Methocarbamol Robaxin also showed signs of addiction when the dose of the drug was increased.
Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents.
Information for Patients Patients should be cautioned that methocarbamol may cause robaxin or dizziness, which may impair their ability to operate motor vehicles or machinery. The blood may be injected with the methocarbamol, addictive the injection may be stopped when the plunger reaches the blood, whichever the physician prefers.
Not Recommended for Subcutaneous Administration. Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that methocarbamol therapy does not adversely affect their ability to robaxin in such 750. Pharmacokinetics In healthy volunteers, the plasma clearance of methocarbamol ranges between 0. It has no direct action on the contractile mechanism of striated muscle, the motor end plate or the nerve fiber. Ordinarily this injection need not be repeated, as Internet administration of the oral form will usually sustain the relief initiated by the injection.
The maintenance dosage may be given by injection dose tubing or milligrams lexapro 30 I.
Carcinogenesis, Mutagenesis, Impairment of external link Long-term studies to evaluate the carcinogenic potential of robaxin have not been performed. Information for Patients Patients should be cautioned that methocarbamol may cause drowsiness or dizziness, which may impair their ability to operate motor vehicles or machinery.
For Product Inquiry call Essentially all methocarbamol metabolites are eliminated in the urine. Pregnancy Teratogenic Effects-Pregnancy Category C Animal reproduction studies have not been conducted with methocarbamol. It does not, however, replace the usual procedure of debridement, tetanus antitoxin, penicillin, tracheotomy, attention to fluid balance, and supportive care.
Its addictive weight is The maintenance dosage may be given by injection into tubing or by I.
Although the amount present in this preparation is well within the limits of safety, caution dictates this contraindication. There have been very rare reports of fetal and congenital abnormalities following in utero exposure to methocarbamol.
Patients should be cautioned about operating machinery, including automobiles, until they are reasonably certain that methocarbamol therapy does not adversely affect their ability to engage in such activities.
Rate of injection should not exceed 3 mL per minute—i. A recumbent position will reduce the likelihood of side reactions.
Blood aspirated into the syringe does not mix with the hypertonic solution. This phenomenon occurs with many other intravenous preparations. The blood may be injected with the methocarbamol, or the injection may be stopped when the plunger reaches the blood, whichever the physician prefers. The total dosage should not exceed 30 mL three vials a day for more than three consecutive days except in the treatment of tetanus.
Caution should be observed in using the injectable form in patients with suspected or known seizure disorders. Information for Patients Patients should be cautioned that methocarbamol may cause drowsiness or dizziness, which may impair their ability to operate motor vehicles or machinery. Because methocarbamol may possess a general CNS-depressant effect, patients should be cautioned about combined effects with alcohol and other CNS depressants. Methocarbamol may inhibit the effect of pyridostigmine bromide.
Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents. Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies to evaluate the carcinogenic potential of methocarbamol have not been performed.
No studies have been conducted to assess the effect of methocarbamol on mutagenesis or its potential to impair fertility. The total dosage should not exceed 30 mL three vials a day for more than three consecutive days except in the treatment of tetanus. Caution should be observed in using the injectable form in patients with suspected or known seizure disorders.
Information for Patients Patients should be cautioned that methocarbamol may cause drowsiness or dizziness, which may impair their ability to operate motor vehicles or machinery. Because methocarbamol may possess a general CNS-depressant effect, patients should be cautioned about combined effects with alcohol and other CNS depressants.
Methocarbamol may inhibit the effect of pyridostigmine bromide. Therefore, methocarbamol should be used with caution in patients with myasthenia gravis receiving anticholinesterase agents.
Carcinogenesis, Mutagenesis, Impairment of Fertility Long-term studies to evaluate the carcinogenic potential of methocarbamol have not been performed.
No studies have been conducted to assess the effect of methocarbamol on mutagenesis or its potential to impair fertility. Pregnancy Teratogenic Effects-Pregnancy Category C Animal reproduction studies have not been conducted with methocarbamol.
It is also not known whether methocarbamol can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. There have been reports of fetal and congenital abnormalities following in utero exposure to methocarbamol. Some events may have been due to an overly rapid rate of intravenous injection. Body as a whole: Anaphylactic reaction, angioneurotic edema, fever, headache Cardiovascular system: Bradycardia, flushing, hypotension, syncope, thrombophlebitis In most cases of syncope there was spontaneous recovery.
Digestive system: Dyspepsia, jaundice including cholestatic jaundice , nausea and vomiting Hemic and lymphatic system: Leukopenia Immune system: Hypersensitivity reactions Nervous system: Amnesia, confusion, diplopia, dizziness or light-headedness, drowsiness, insomnia, mild muscular incoordination, nystagmus, sedation, seizures including grand mal , vertigo The onset of convulsive seizures during intravenous administration of methocarbamol has been reported in patients with seizure disorders.
The psychic trauma of the procedure may have been a contributing factor. Overdose of methocarbamol is frequently in conjunction with alcohol or other CNS depressants and includes the following symptoms: nausea, drowsiness, blurred vision, hypotension, seizures, and coma.
In post-marketing experience deaths have been reported with an overdose of methocarbamol alone or in the presence of other CNS depressants, alcohol or psychotropic drugs. Treatment Management of overdose includes symptomatic and supportive treatment. Supportive measures include maintenance of an adequate airway, monitoring urinary output and vital signs, and administration of intravenous fluids if necessary.
The usefulness of hemodialysis in managing overdose is unknown. Total adult dosage should not exceed 30 mL 3 vials a day for more than 3 consecutive days except in the treatment of tetanus. If the condition persists, a like course may be repeated after a drug-free interval of 48 hours. Dosage and frequency of injection should be based on the severity of the condition being treated and therapeutic response noted. For the relief of symptoms of moderate degree, one dose of 1 gram one 10 mL vial may be adequate.
Ordinarily this injection need not be repeated, as the administration of the oral form will usually sustain the relief initiated by the injection. Care should be exercised to avoid vascular extravasation of this hypertonic solution, which may result in thrombophlebitis. It is preferable that the patient be in a recumbent position during and for at least 10 to 15 minutes following the injection.
Directions for Intramuscular Use When the intramuscular route is indicated, not more than five mL one-half vial should be injected into each gluteal region.
The injections may be repeated at eight hour intervals, if necessary. When satisfactory relief of symptoms is achieved, it can usually be maintained with tablets.
Not Recommended for Subcutaneous Administration. Special Directions for Use in Tetanus There is clinical evidence which suggests that methocarbamol may have a beneficial effect in the control of the neuromuscular manifestations of tetanus.
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The tablet version is more common in cases of full body muscle spasms. It's a good way to help relax your pet in general. The injectable version of the medicine is better in cases in which a single muscle or part of the body is affected by the spasm. In cases of the tablet form of the drug, vets typically recommend providing your pet with a dosage of about 7 to 20 milligrams per pound, given two or three times per day.
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