In the first case, the disease occurs suddenly and the animals quickly die. The main toxic factor of this microbe is epsilon toxin. The causative agent of the disease is an anaerobic microbe from the family Bacillaceae, genus Clostridium Cl.
Forms spores. The disease in sheep proceeds super-acutely, acutely and chronically. The incubation period depends on the degree of intoxication and the resistance of the organism. With artificial infection, it is hours; according to our observations - from 60 minutes to 12 hours.
With a hyperacute course of the disease, buy vardenafil pills within hours , clinical signs usually do not appear. Mostly men are ill times more often than women at the age of years. However, the disease also occurs in children and the elderly. Macroscopically, grayish-white dense tubercles in the form of grains are determined on the surface of the lungs.
Microscopic examination reveals a CHIC-positive substance proteoglycans, glycoproteins, glycolipids are stained with Schiff's reagent in purple or lilac-red color , filling the alveoli and bronchioles. Birefringent crystals are found.
There are no signs of inflammation. CONTACT US Symptoms of alveolar proteinosis of the lungs: NeredThe main reason for the patient to see a doctor is slowly but steadily progressing shortness of breath, which may be accompanied by a cough with scanty, yellowish sputum, sometimes hemoptysis, subfebrile body temperature, chest pain, cyanosis depending on the degree of respiratory insufficiency , sweating, weight loss, fast fatigue.
An objective examination determines the shortening of the percussion tone, mainly in the lower sections of the lungs. Clinical and biochemical analyzes do not contain any signs characteristic of levitra pulmonary proteinosis. In some patients, an increase in the level of cholesterol, calcium is determined in the blood. These changes are usually bilateral. Bronchoscopy is uninformative.
The diffusion capacity of the lungs decreases, restrictive ventilation disorders slowly progress, and hypoxemia is detected during exercise. In the terminal stages, a cor pulmonale is formed.
Diagnosis of alveolar proteinosis of the lungs: A definite diagnosis can only be established with the help of a lung biopsy. This disease should be differentiated from other disseminated processes in the lungs.
In , lung lavage was first used in four patients with alveolar proteinosis. A patient undergoing lung lavage is intubated. Under general anesthesia, one lung is ventilated with pure oxygen; and the second lung lobe, segment is washed with saline containing heparin and enzymes N-acetylcysteine, streptase, etc.
As a rule, after an effective lavage, there is a positive clinical, radiological and functional dynamics. Depending on the rate of progression of the disease, lung lavage is repeated after months.
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